The 1970s brought a new understanding of the biological and intellectual impact of environmental crises on human beings, and as efforts to prevent ecological and human degradation aligned, a new literature of sickness emerged. “Ecosickness fiction” imaginatively rethinks the link between ecological and bodily endangerment and uses affect and the sick body to bring readers to environmental consciousness. Tracing the development of ecosickness through a compelling archive of modern U.S. novels and memoirs, this study demonstrates the mode’s crucial role in shaping thematic content and formal and affective literary strategies. Examining works by David Foster Wallace, Richard Powers, Leslie Marmon Silko, Marge Piercy, Jan Zita Grover, and David Wojnarowicz, Heather Houser shows how these autho