Mikan Sakura and Hotaru Imai are inseparable best friends, even if it seems like the latter does not reciprocate the same sentiment. Mikan naively believes that her aloof best friend would always be by her side until Hotaru decides to depart for Tokyo to attend Alice Academy. The school is home to gifted children who possess unique abilities known as Alices. Heartbroken and feeling abandoned, Mikan runs away from home in pursuit of her friend, hoping that she too can enroll in the prestigious institution. As Mikan gets accepted as a student at Alice Academy and reunites with her friend, she quickly learns that the academy is not all fun and games. The school itself is divided into a hierarchy system based on the strength of their Alice, behavior, and academic performance, as well as class